Colicins and other bacteriocins with established modes of action.
نویسنده
چکیده
INTRODUCTION ........................................................................................................ 125 COLICIN E2 AND E3 AND CLOACIN DF!3 ........................................................ !26 Mode of Action .......................................................................................................... 126 General Structure ...................................................................................................... 127 Immunity System ...................................................................................................... 127 Functional and Structural Domains ........................................................................ 128 COLICINS A, E! la, Ib, and K .................................................................................. 129 Mode of Action .......................................................................................................... 129 Structural Features .................................................................................................... 131 Immunity System ...................................................................................................... 132 COLICIN L .................................................................................................................... 1 33 COLICIN IV,[ ................................................................. ................................................. 133 TO THE TARGET ........................................................................................................ 134 Role of Receptors ....................................................................................... ............... 134 Possible Role 0/ Proteases ........................................................................................ 134 Colicin Uptake .......................................................................................................... 1 35 PESTICIN A 1 122 ....... . . ................ ............ . . . ............................ . . . ........... ........................ 136 STAPHYLOCOCCIN 1580 .......................................................................................... 137 BUTYRICIN 7423 ... . . . .......... . . ........ . . . . . . ........... .................. ........... . . . . ............ ...... . . . . . . .... 138 PYOCIN Rl .................................................................................................................. 138 PYOCIN AI'41 .............................................................................................................. 139 MEGACIN A-216 .......................................................................................................... 140 CONCLUDING REMARKS ............. ......................................................................... 140
منابع مشابه
Escherichia coli Bacteriocins: Antimicrobial Efficacy and Prevalence among Isolates from Patients with Bacteraemia
Bacteriocins are antimicrobial peptides generally active against bacteria closely related to the producer. Escherichia coli produces two types of bacteriocins, colicins and microcins. The in vitro efficacy of isolated colicins E1, E6, E7, K and M, was assessed against Escherichia coli strains from patients with bacteraemia of urinary tract origin. Colicin E7 was most effective, as only 13% of t...
متن کاملDetection of Colicin genes by PCR in Escherichia coli isolated from cattle in Shiraz-Iran
A variety of probiotic bacteria have been tested to control animal and foodborne pathogenic bacteria in livestock. The mechanism of inhibition of pathogenic bacteria for several of those probiotic microorganisms is mediated by the production of bacteriocins. Colicins are probably the group of bacteriocins that have been most thoroughly characterized. Colicins are antimicrobial proteins produced...
متن کامل3 Molecular Evolution of Bacteriocins in Gram-Negative Bacteria
The study of molecular evolution has become a valuable tool in understanding the origin of life and the speciation of organisms, with the focus on changes in DNA and protein sequence and their functions. Interest in studying the molecular evolution of bacteriocins, the narrow-spectrum peptide antimicrobials, was elicited due to the broad diversity and abundance of these proteins. The availabili...
متن کاملThe ecological role of bacteriocins in
TRENDS IN MICROBIOLOGY 129 VOL. 7 NO. 3 MARCH 1999 Bacteriocins are one of the most abundant and diverse classes of antimicrobial molecules, having been detected in all major lineages of Eubacteria and in Archaebacteria1–3. They are potent, often highly specific toxins that are usually produced during stressful conditions and result in the rapid elimination of neighboring cells that are not imm...
متن کاملThe ecological role of bacteriocins in bacterial competition.
Bacteriocins are an abundant class of antimicrobial molecules that appear to mediate population dynamics within species. The bacteriocins of Escherichia coli have served as a model for exploring the ecological role of these potent toxins. Studies suggest that colicins provide a competitive edge in nutrient-poor environments and that there might be a trade-off between the costs and benefits of c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Annual review of microbiology
دوره 36 شماره
صفحات -
تاریخ انتشار 1982